After pursuing Kevin Wendell Crumb and the multiple identities that reside within. David Dunn finds himself locked in a mental hospital alongside his archenemy, Elijah Price and must contend with a psychiatrist who is out to prove the trio do not actually possess superhuman abilities 故事讲述玻璃先生（塞缪尔·杰克逊 饰）发现大卫·杜恩（布鲁斯·威利斯 饰）正在追捕凯文·温德尔·克鲁伯（詹姆斯·麦卡沃伊 饰）的人格分裂化身之一“野兽”，而他手中则掌握对二者来说至关重要的秘密......